Genetic mutations occur everyday in our cells, but the vast majority of them are repaired. New research finds DNA repair is not on PAR in HD cells, causing mutations to build up in people with HD.

For many with Huntington’s disease, recognising faces, navigating familiar places, or reading can be difficult. Scientists studied how and when HD affects how the brain processes what we see—crucial ...

Dr. Sarah Hernandez is the Director of Research Programs at the Hereditary Disease Foundation (HDF). She carried out her ...

A new study shows that lowering MSH3, a key DNA repair protein, with antisense oligonucleotide (ASO) therapy can stop CAG repeat expansions in HD patient-derived brain cells. This could be a promising ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community. This is a fallback page – if you see it something has gone wrong – email [email protected] with ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community. This is a fallback page – if you see it something has gone wrong – email [email protected] with ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community. This is a fallback page – if you see it something has gone wrong – email [email protected] with ...

Huntington’s disease research news. In plain language. Written by scientists. For the global HD community. This is a fallback page – if you see it something has gone wrong – email [email protected] with ...

In plain language. Written by scientists. For the global HD community.

Imagine a busy intersection - traffic is carefully orchestrated with different colored lights, telling drivers when to stop and when to go. If a signal turns yellow, drivers know that the light is in ...

Huntington’s disease disrupts genetic "traffic lights," keeping genes green when they should be red. These genetic traffic jams may act to speed brain cell aging and faulty traffic cops ...