As a steady lake-effect snowstorm pounded Orchard Park, the Bills did the same to the visiting San Francisco 49ers. Led on ...

How thorough was the Buffalo Bills’ 35-10 win over the San Francisco 49ers on Sunday night? Quarterback Josh Allen was ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.

On first-and-goal at the San Francisco 7-yard line, Josh Allen, Amari Cooper and ... Josh Allen connected for one of the most ...

Follow along for updates throughout the game as the Buffalo Bills take on the San Francisco 49ers at snowy Highmark Stadium.

The first season of major conference expansion has produced an intriguing set of championship games this week, and not just ...

The Buffalo Bills will not have rookie wide receiver Keon Coleman in the lineup Sunday night against the San Francisco 49ers.

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

"The Bills are dangerous because they can win in different ways – via Allen’s arm or tailback James Cook’s running ability or the post-catch yards by receiver Khalil Shakir or because of a ...

The Buffalo Bills, supposedly in a reset/transition/pivot year after moving on from myriad veterans during the offseason, are ...

The BetMGM bonus code is FPB50 for NFL betting and it offers an exclusive welcome bonus worth up to $1,550 for the Buffalo ...

After the Miami Dolphins lost to the Packers in Green Bay on Thursday, the Bills can clinch the AFC East with a win on Sunday ...