Including the playoff game, Shanahan’s 49ers have beaten McVay’s Rams in 10 of 16 games. The two worked together for a year ...

Our expert picks and analysis on the best prop bets you should make for the Los Angeles Rams vs. San Francisco 49ers on ...

NFL Week 15 odds, picks, predictions, TV channel, streaming for Thursday Night Football game between Los Angeles Rams and San ...

Already missing five starters during the blowout loss to the Bills, San Francisco lost star running back Christian McCaffrey ...

The San Francisco 49ers still have an outside shot to make the NFL playoffs, but as their chances dip despite a blowout win ...

The 49ers returned to form on both sides of the ball Sunday, led by a season-high 151 receiving yards from George Kittle.

The tight end, who tore his ACL in January, could see game action for the first time this season on Thursday night in San ...

Kyle Shanahan updated the 49ers’ injury outlook and RB Isaac Guerendo’s status immediately following the win vs. the Bears.

San Francisco 49ers linebacker De'Vondre Campbell threatened Bills receiver Mack Hollins for pulling on his dreadlocks during ...

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

It has been a disaster of the season for the San Francisco 49ers and now they face another team in the Chicago Bears that has ...

The Los Angeles Rams and San Francisco 49ers are both trailing the Seattle Seahawks in the NFC West, and they play a crucial matchup on Thursday Night Football ...