"This flagrant assault, which forms part of a deliberate policy pursued by the Israeli entity to inflame tensions, spread chaos, and undermine security and stability in Syria, constitutes a blatant violation of the United Nations Charter and international humanitarian law," it added.

Israel said it took military action in support of Syria’s Druze population which has been involved in deadly clashes with Syrian government forces in recent days. The move sent US officials scrambling to prevent a larger escalation between the two Middle East nations.

The Israel Defense Forces (IDF) said the Damascus headquarters served as a command center for deploying regime forces to Suwayda, a southern Syrian region gripped by days of deadly clashes between government troops, Druze militias, and Bedouin groups.

The Israeli military said it had "struck the entrance gate" of the Syrian regime's military headquarters complex in Damascus.

Clan fighters gathered in the Syrian capital Damascus on Saturday to support Bedouin militants in their clashes with Druze armed factions in the southern province of Sweida despite calls for a ceasefire.

Israel carried out a series of powerful strikes on the Syrian capital Damascus Wednesday, escalating a campaign it says is in support of an Arab minority group involved in deadly clashes with Syrian government forces.

The World’s Host Marco Werman speaks with Istanbul-based journalist Ruth Michaelson about unrest in Syria amid clashes between minority groups, government military involvement and Israeli airstrikes in the country.

The attack follows a wave of Israeli strikes on Syrian government forces during two days of sectarian clashes between local Druze and Bedouin populations.

Clashes raged in the southern Syrian city of Sweida on Wednesday after a ceasefire between government forces and Druze armed groups collapsed and as Israel threatened to escalate its involvement, saying it's in support of the Druze religious minority.

Secretary of State Rubio says the U.S. is "very concerned" by expanding Israeli strikes targeting Syria's new government, and he wants "the fighting to stop."

Government forces that were initially sent to restore order but effectively sided with the Bedouins against the Druze were redeployed to halt renewed fighting that erupted Thursday in the southern province of Sweida. The violence also drew airstrikes against Syrian forces by neighboring Israel before a truce was reached.