San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.

After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

The Bills got the job done in their own snowy backyard against the 49ers in NFL Week 13 action. In a 35-10 final, the Bills ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The Buffalo Bills proved snow can't stop them, which we've seen time and again in Western New York (hey, why are they ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

The most recent instance of a quarterback scoring on his own pass was when Marcus Mariota had his pass batted up into the air ...

A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.