Investigations into the reason why Shigella is enclosed within neutrophil vacuoles led Weinrauch and Zychlinsky to discover how the neutrophil can neutralize not only Shigella but also other ...

A key function of neutrophils is to attack and kill bacteria at sites of infection. Bacteria are phagocytosed and fusion of phagocytic vacuoles with neutrophil granules exposes the bacteria to a ...

To assess the sizes of phagocytic vacuoles and their contents, 5 × 10 7 fresh human neutrophils were mixed with 5 × 10 8 IgG-opsonized S. aureus cells in a rapidly stirred chamber at 37 °C.