It was previously demonstrated that the HIV-1 integrase (IN)-interacting host factor INI1/SMARCB1 binds to HIV-1 IN through its Rpt1 domain of INI1 (INI1-Rpt1) and plays a key role in assembly and ...

Phase 1 Data Indicate Potential for Use of Once-Yearly Lenacapavir for HIV Prevention, with Plans to Launch a Phase 3 Trial in 2H 2025 – ...

Merck Sharp & Dohme LLC has synthesized viral replication inhibitors reported to be useful for the treatment of respiratory syncytial virus and metapneumovirus infections.

The complex retroviruses, such as HIV, encode additional trans-regulating factors or contain cis-regulating elements, thereby influencing the type and amount of transcribed RNA. The whole viral ...

In keeping with recent conferences, several studies of investigational agents, some of them near approval and some in the earliest phases of development, were presented. This summary focuses on ...