In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...

We calculated the average gene expression levels in glycolysis and OXPHOS as indicators of glucose supply and ... Discard the blocking solution, add the primary antibody, and incubate overnight at 4 ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

Antithyroid antibodies target specific parts of the thyroid gland, including: Thyroid peroxidase (TPO). TPO is an enzyme that plays an important role in making thyroid hormones. Thyroglobulin (Tg).

Antivenom (often spelled “antivenin”) is an antibody product that can disable a particular venom’s toxins. If injected quickly after a bite or sting, the antibodies in antivenom neutralize the venom, ...

Bispecific antibodies seem to be all the rage at the minute. Their ability to deliver targeted therapeutics to patients with a two-in-one approach by simultaneously binding to two different antigens ...

Current therapies mainly focus on mitigating early inflammatory response through proinflammatory cytokines and pathways targeting, including corticosteroids, TNF-α inhibitors, IL-1β monoclonal ...

Autoimmune diseases are conditions in which your immune system mistakenly damages healthy cells in your body. Types include rheumatoid arthritis, Crohn’s disease, and some thyroid conditions ...

They also promote growth, development, and maturation of the brain and nervous system. Antibodies serve a purpose in your body; they defend against bacteria, viruses, and toxins. In an individual with ...

As a mechanism of cell death, ferroptosis has gained popularity since 2012. The process is distinguished by iron toxicity and phospholipid accumulation, in contrast to autophagy, apoptosis, and other ...