A 2004 study in Japan found that 9 of 50 children with influenza A (H3N2) virus infection who had been treated with oseltamivir (18 percent) had a virus with a drug-resistance mutation in the ...

Oseltamivir usage is associated with a 92% reduction in the incidence of laboratory-confirmed clinical influenza in frail, elderly people living in nursing homes.

Influenza A (H5N1) virus causes severe disease in humans and poses an unprecedented pandemic threat. 1–3 The neuraminidase inhibitor oseltamivir constitutes an important treatment option, and ...

Saturday, March 15, 2025. News & Perspective Drugs & Diseases CME & Education Video Drugs & Diseases CME & Education Video ...

Oseltamivir clinical trial data. Monto and colleagues performed a meta-analysis of published and unpublished randomized clinical trials conducted from 1997 to 2001 — made available through ...

Oseltamivir for Influenza in Adults and Children: Systematic Review of Clinical Study Reports and Summary of Regulatory Comments . Jefferson T, Jones M, Doshi P, Spencer EA, Onakpoya I, Heneghan CJ ...

Early use of oseltamivir in hospitalized children with influenza led to better outcomes, according to the results of a large study published in JAMA Pediatrics. Co-author Patrick S. Walsh, MD, MS ...

Baloxavir, compared with oseltamivir, was associated with lower health care resource utilization and costs in patients with influenza, particularly those at high risk of secondary complications.

Still, oseltamivir is a safe drug, she said, and given the uncertainties over how severe a case of H5N1 could become, use of the antiviral makes sense. Public health authorities agree.

Oseltamivir was also not associated with a reduced risk for hospitalization among older populations (mean age, 65 years and older; RR, 0.99; 95 percent CI, 0.19 to 5.13) ...

Oseltamivir ranks as the most commonly prescribed treatment for flu, the CDC says. A study published last year found the drug made up 99.8% of flu antivirals prescribed to kids.

Oseltamivir shows dose-linear kinetics, with an elimination half-life of approximately 7.7 hours in healthy individuals. Oseltamivir carboxylate is eliminated primarily by kidney via glomerular ...