The EMBO Journal14h
Targeting to BMP9 to restrain flare-up of fibrodysplasia ossificans progressiva
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease characterized primarily by the formation of heterotopic ...
The EMBO Journal8d
BBSome-deficient cells activate intraciliary CDC42 to trigger actin-dependent ciliary ectocytosis
CDC42 drives ciliary actin polymerization and ectocytosis. The hyperactivation of ciliary CDC42, along with excessive ...
The EMBO Journal13d
PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...
The EMBO Journal13d
Soul Men and Women—what must science do to regain public trust?
Whether it amounts to anything in the very long run, preserving this planet and its occupants safely for the next hundred ...
The EMBO Journal8d
New players and targets in mannose 6-phosphate-dependent lysosomal sorting
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...
The EMBO Journal1d
Fibrillarin homologs regulate translation in divergent cell lineages during planarian homeostasis and regeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. fbl-1 and fbl-2 are required for planarian ...
The EMBO Journal5d
Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Chromatin remodeling is likely to be required ...
The EMBO Journal6d
The TGF-β mimic TGM4 achieves cell specificity through combinatorial surface co-receptor binding
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The immunoregulatory cytokine TGF-β is ...
The EMBO Journal9d
Gpr54 deletion accelerates hair cycle and hair regeneration
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. GPR54, or KiSS-1R (Kisspeptin receptor), is ...
The EMBO Journal12d
Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. PCNA is a master coordinator of many ...
The EMBO Journal16d
Novel integrated multiomics analysis reveals a key role for integrin beta-like 1 in wound scarring
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. A high-resolution spatial multiomics approach ...
The EMBO Journal19d
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Eukaryotic mRNAs are transcribed, processed, ...