After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

The Buffalo Bills didn't just beat the San Francisco 49ers on Sunday night. They destroyed the reigning NFC champions. The ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

This is the live blog for the 49ers' Week 13 road game against the Buffalo Bills. This will be updated frequently with ...

The Bills are a Super Bowl contender and the 49ers somehow probably aren’t even a playoff team. That’s how Sunday night’s ...

Fans can stream the Buffalo Bills 2024 season on fuboTV, and get cheap tickets to see the Bills from SeatGeek. Fanatics has a ...