The San Francisco 49ers placed running back Christian McCaffrey on injured reserve Tuesday a day after coach Kyle Shanahan ...

The San Francisco 49ers have signed a former New York Jets running back to replace the injured Christian McCaffrey and Jordan ...

The 49ers lost running back Christian McCaffrey for the season with a knee injury. His backup, Jordan Mason, will also be ...

Many are curious about the 49ers’ injury updates, which put Christian McCaffrey and Jordan Mason on IR. Fans now wonder how ...

The San Francisco 49ers’ dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

San Francisco 49ers running back Christian McCaffrey and top backup Jordan Mason are being placed on injured reserve.

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...

San Francisco 49ers star running back Christian McCaffrey suffered a PCL injury and is expected to miss six weeks, head coach ...

San Francisco 49ers running back Jordan Mason is going on injured reserve, head coach Kyle Shanahan announced.

Suddenly, the Niners' starting running back on Sunday against the Chicago Bears will be rookie Isaac Guerendo with practice ...

The San Francisco 49ers entered this season with lofty aspirations. For the most part, their hopes have been dashed -- and ...

Running back Christian McCaffrey will go on injured reserve with a posterior cruciate ligament strain that may not need ...