Prophecy Valya rarely uses the Voice. Valya has a more complex and ambitious nature, making her an interesting vessel for this power. In Season 1, Episode 3, Valya appears in a flashback sequence. We learn about her difficult life on her icy home planet.

Valya Harkonnen has a mysterious plan for her nephew, House Harkonnen, and the High Council at Landsraad in Dune: Prophecy episode 4 "Twice Born".

In this third installment, "Sisterhood Above All," we begin with a shellshocked Valya exiting the palace gates on Salusa Secundus with Sister Theodosia. Fearing that the Sisterhood's hold on the great houses is quickly slipping, they must act fast to regain control, especially with the Emperor's House Corrino.