San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The Chiefs were the first team to clinch an NFL playoff berth, but the Bills can one-up them by sealing the AFC East with a ...

In eight season’s San Francisco 49ers tight end George Kittle never played in Buffalo at Highmark Stadium. Despite the loss ...

Lake effect snow is slamming the Great Lakes, with seven states from Wisconsin to New York under snow alerts on Monday.

Bills quarterback Josh Allen and head coach Sean McDermott celebrated by making snow angels after Buffalo clinched its fifth ...

Buffalo Bills quarterback Josh Allen enhanced his MVP credentials with a win over the San Francisco 49ers.

Frigid air was expected to move over the eastern third of the U.S. by Monday, with temperatures about 10 degrees below ...

Parts of the Great Lakes region saw new snow Monday and faced the prospect of even more this week after U.S. travelers ...

THE BUFFALO BILLS ... The Bills dashed through the snow ... and past the 49ers, 35-10, in a game that saw and Josh ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday Night Football, rumbling past them 35-10. Not only did this win ...

The San Francisco 49ers entered the 2024 NFL season with Super Bowl aspirations. 12 games in to the season, though, the 49ers ...