Thus the anti-Influenza activity of NV-387 given orally was substantially superior to all three of the approved anti-influenza drugs, namely Tamiflu, Rapivab, and Xofluza.

Objective: To determine the effect of oseltamivir (75mg twice daily) on time to return to baseline health, sleep and activity in patients with laboratory-confirmed influenza infection. Patients ...

With influenza season coming up, this month’s Pharmacology Consult will review the prophylaxis and drug treatment of this common infectious disease. Information on immunization for the coming ...

But the possibility of widespread oseltamivir resistance has been a concern for several years. Structural analysis of the influenza neuraminidase predicted that resistance to oseltamivir would be ...

It has shown therapeutic activity in preclinical models of influenza A and B virus infections, ... (H1N1) viruses in 2008–2009 1 and by community clusters of oseltamivir-resistant influenza A ...

'Normal seasonal activity', as measured by these surveillance schemes, corresponds to the term 'circulating' in NICE's technology appraisal guidance on flu treatment – zanamivir, amantadine and ...

To evaluate the safety and antiviral activity of the treatment, patients in the TOPAZ trial (N=292) were randomized to receive pimodivir 300mg or 600mg, pimodivir 600mg plus oseltamivir 75mg, or ...

Early treatment with this potent antiviral drug not only reduces the duration and severity of influenza symptoms, it also may help reduce the overall burden of influenza on society. News & Perspective ...