Head coach Kyle Shananhan said running back Christian McCaffrey suffered a knee injury during the team's 35-10 loss to the ...

The San Francisco 49ers have been decimated by injuries, but their struggles this year go beyond that. The team does not look ...

In eight season’s San Francisco 49ers tight end George Kittle never played in Buffalo at Highmark Stadium. Despite the loss ...

The San Francisco WAG All-Star has fun and looks good in the snow on Sunday night, but she’s ready to burn her creation.

During the San Francisco 49ers 35-10 loss to the Buffalo Bills on Sunday night, superstar running back Christian McCaffrey ...

NFL Week 14 odds, picks, predictions, TV channel, streaming information for Sunday football game between Chicago Bears and ...

The San Francisco 49ers dropped their record to 5-7 after a 35-10 loss against the Buffalo Bills in Week 13. Today, Pro ...

Buffalo Bills quarterback Josh Allen enhanced his MVP credentials with a win over the San Francisco 49ers.

The Buffalo Bills dismantled the San Francisco 49ers 35-10 at Highmark Stadium, and clinched the AFC East in the process.

Watch the best touchdowns from Week 13 of the 2024 NFL season. Watch all of Buffalo Bills running back James Cook's best ...

Matthew Berry, Jay Croucher and Connor Rogers dive into the ramifications of star Christian McCaffrey's latest injury, ...

Replacing McCaffrey won't be easy for fantasy football managers, but these three running backs present the most viable ...