The nitrogen metabolism pathway overlaps with the biosynthesis of arginine and proline, with glutamate as the shared precursor. Histidine biosynthesis branches off the pentose phosphate metabolism.

The results of a new study show that suppressing KCTD20, which responds to the neurotransmitter glutamate, activates a mechanism for expelling tau proteins.

Urinary glutamate enrichment was not detected ... To our knowledge, this is the first multistable isotope study quantifying the metabolism of arginine in enterally fed human preterm infants.