With the exception of N-acetylgalactosamine (GalNAc), which mediates liver targeting, there are no safe and effective means of delivering oligonucleotide drugs to other relevant target cells and ...
Silence Therapeutics (NASDAQ:SLN – Get Free Report) is expected to be announcing its earnings results before the market opens ...
The GalNAc platform is made up of two approaches ... Both STP705 and STP707 are made of two siRNA oligonucleotides that hit transforming growth factor beta 1 (TGF-β1) and cyclooxygenase 2 ...
The results come from the phase 1b/2a RestorAATion-2 study of WVE-006, a GalNAc-conjugated oligonucleotide that is designed to correct a mutation in mRNA associated with AATD that prevents ...
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Goldman Sachs Initiates Coverage of Silence Therapeutics plc - Depositary Receipt () (SLN) with Sell RecommendationSilence's proprietary messenger RNAi GOLD™ (GalNAc Oligonucleotide Discovery) Platform can be used to create siRNAs that precisely target and silence disease-associated genes in the liver ...
Dosing underway in INLIGHT trial of WVE-007 in obesity with clinical data expected in 2H 2025; enrollment complete in first ...
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