Pala is a small, mostly Native American community and census-designated place located within the Pala Indian Reservation in San Diego County, California. For centuries a traditional gathering place of native peoples. The Mission San Antonio de Pala or Pala Mission was established in Pala by early 19ᵗʰ century as an asistencia or sub-miss…Pala is a small, mostly Native American community and census-designated place located within the Pala Indian Reservation in San Diego County, California. For centuries a traditional gathering place of native peoples. The Mission San Antonio de Pala or Pala Mission was established in Pala by early 19ᵗʰ century as an asistencia or sub-mission.